The NICE Headache Guidelines have stated that a Triptan
can be considered and a recently published retrospective database showed no increase in birth defects above the natural background
rate in pregnant women who are taking Sumatriptan. If drugs that are known to be safe during pregnancy
are not effective, then the benefits of Sumatriptan should be discussed against the potential risks of using any drug in pregnancy
against a background of this reassuring data. If Triptans are to be used, then the patient should issue
written consent along the prescribing guidelines. It would be sensible to avoid use in the first Trimester.